Try searching バーチャルYouTuber 同人 マンコ on DLsite (R18). If that fails, the doujin may have been deleted or the title misremembered beyond recovery. If you can provide any additional context — such as the platform where you saw this string (Twitter, 4chan, a forum), the approximate year, or any character names — I can help narrow down the search further.
The substring stands out — in Japanese, マンコ (manko) is a vulgar slang for vagina. This appears in adult doujinshi (ero doujin). "Tsukawas" could be 使わす (tsukawasu, causative of "to use"). doujindesutviribitarigalnimankotsukawas upd
But "Iribitarigal" doesn’t match any known series. Could be "Iribitaru Gal" (イリビタルギャル) — which might be a misspelling of "Irregular Gal" or "Virtual Gal" (バーチャルギャル → "bācharu garu" → mis-typed as ribitaru). The substring stands out — in Japanese, マンコ
Thus, a possible original title: Translation: "It's a doujin TV Iribitarigal 20,000 use [vulgar] – updated" But "Iribitarigal" doesn’t match any known series